Suivi thérapeutique des médicaments (I). Les principes [Principles of therapeutic drug monitoring]

Details

Serval ID
serval:BIB_56FB6F49D00F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Suivi thérapeutique des médicaments (I). Les principes [Principles of therapeutic drug monitoring]
Journal
Revue Médicale Suisse
Author(s)
Widmer N., Csajka C., Werner D., Grouzmann E., Decosterd L.A., Eap C.B., Biollaz J., Buclin T.
ISSN
1660-9379
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
4
Number
165
Pages
1644-1668
Language
french
Abstract
Requesting a blood level measurement of a drug is part of the global approach known as "Therapeutic Drug Monitoring". Diverse situations require this monitoring approach, such as inadequate response to treatment or organ failure. Every drug however does not possess all the characteristics for a TDM program. The therapeutic range of a TDM drug has indeed to be narrow and its interindividual pharmacokinetic variability to be wide. As the development of new drugs is currently slowing down, the precise management of existing treatments certainly deserves progress, but needs however to be applied rationally, starting from a valid indication to blood sampling, and ending with a sound dosage adaptation decision.
Keywords
Anti-Bacterial Agents, Anti-Retroviral Agents, Anticonvulsants, Antineoplastic Agents, Antiparasitic Agents, Antitubercular Agents, Cardiovascular Agents, Dose-Response Relationship, Drug, Drug Monitoring, Humans, Immunosuppressive Agents, Pharmaceutical Preparations, Product Surveillance, Postmarketing, Psychotropic Drugs
Pubmed
Create date
22/01/2009 10:13
Last modification date
20/08/2019 14:11
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