Using 80 kVp versus 120 kVp in perfusion CT measurement of regional cerebral blood flow.

Details

Serval ID
serval:BIB_52B23D9B3FD1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Using 80 kVp versus 120 kVp in perfusion CT measurement of regional cerebral blood flow.
Journal
AJNR. American journal of neuroradiology
Author(s)
Wintermark M., Maeder P., Verdun F.R., Thiran J.P., Valley J.F., Schnyder P., Meuli R.
ISSN
0195-6108
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
21
Number
10
Pages
1881-4
Language
english
Notes
Publication types: Journal Article - Publication Status: ppublish
Abstract
Perfusion CT studies of regional cerebral blood flow (rCBF), involving sequential acquisition of cerebral CT sections during IV contrast material administration, have classically been reported to be achieved at 120 kVp. We hypothesized that using 80 kVp should result in the same image quality while significantly lowering the patient's radiation dose, and we evaluated this assumption. In five patients undergoing cerebral CT survey, one section level was imaged at 120 kVp and 80 kVp, before and after IV administration of iodinated contrast material. These four cerebral CT sections obtained in each patient were analyzed with special interest to contrast, noise, and radiation dose. Contrast enhancement at 80 kVp is significantly increased (P < .001), as well as contrast between gray matter and white matter after contrast enhancement (P < .001). Mean noise at 80 kVp is not statistically different (P = .042). Finally, performance of perfusion CT studies at 80 kVp, keeping mAs constant, lowers the radiation dose by a factor of 2.8. We, thus, conclude that 80 kVp acquisition of perfusion CT studies of rCBF will result in increased contrast enhancement and should improve rCBF analysis, with a reduced patient's irradiation.
Keywords
Brain, Cerebrovascular Circulation, Contrast Media, Humans, Radiation Dosage, Regional Blood Flow, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
29/02/2008 17:45
Last modification date
20/08/2019 14:08
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