Interpretation and use of FRAX in clinical practice.

Details

Serval ID
serval:BIB_50574799B32C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Interpretation and use of FRAX in clinical practice.
Journal
Osteoporosis International
Author(s)
Kanis J.A., Hans D., Cooper C., Baim S., Bilezikian J.P., Binkley N., Cauley J.A., Compston J.E., Dawson-Hughes B., El-Hajj Fuleihan G., Johansson H., Leslie W.D., Lewiecki E.M., Luckey M., Oden A., Papapoulos S.E., Poiana C., Rizzoli R., Wahl D.A., McCloskey E.V.
Working group(s)
Task Force of the FRAX Initiative
Contributor(s)
Eugene M., Neil B., Jonathan A., Sanford B., Dennis B., Kleerekoper M., Krieg MA., Langdahl B., Laster A., Leib E., Masud T., McClung M., Rizzoli R., Saag K., Siris E., Lewiecki EM., Compston J., Adams JA., Adler R., Bauer D., Glen B., Patricia C., Adolfo DP., Didier H., Kanis JA., Krieg MA., Hans D., Leslie W., Moayyeri A., Josse R., Kendler D., Khan A., Lentle B., Lorenc R., Masri B., Miller P., Cauley J., Fuleihan Gel-H., Arabi A., Calderon A., Chen Z., Bee Chinoh S., Curtis J., Danielson M., Fujiwara S., Hanley D., Heikki K., Annie K., Lesnyak O., Looker A., Luckey M., Mellstrom D., Nieves J., Wojciech P., Rassi RE., Rizzoli R., Ragi-Eis S., Schott-Pethelaz AM., Silverman S.
ISSN
1433-2965 (Electronic)
ISSN-L
0937-941X
Publication state
Published
Issued date
2011
Volume
22
Number
9
Pages
2395-2411
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review Publication Status: ppublish
Abstract
The introduction of the WHO FRAX® algorithms has facilitated the assessment of fracture risk on the basis of fracture probability. Its use in fracture risk prediction has strengths, but also limitations of which the clinician should be aware and are the focus of this review
INTRODUCTION: The International Osteoporosis Foundation (IOF) and the International Society for Clinical Densitometry (ISCD) appointed a joint Task Force to develop resource documents in order to make recommendations on how to improve FRAX and better inform clinicians who use FRAX. The Task Force met in November 2010 for 3 days to discuss these topics which form the focus of this review.
METHODS: This study reviews the resource documents and joint position statements of ISCD and IOF.
RESULTS: Details on the clinical risk factors currently used in FRAX are provided, and the reasons for the exclusion of others are provided. Recommendations are made for the development of surrogate models where country-specific FRAX models are not available.
CONCLUSIONS: The wish list of clinicians for the modulation of FRAX is large, but in many instances, these wishes cannot presently be fulfilled; however, an explanation and understanding of the reasons may be helpful in translating the information provided by FRAX into clinical practice.
Keywords
Algorithms, Bone Density, Female, Fractures, Bone/epidemiology, Fractures, Bone/etiology, Humans, Male, Models, Statistical, Osteoporosis/complications, Practice Guidelines as Topic, Risk Assessment/methods, Risk Factors, World Health, World Health Organization
Pubmed
Web of science
Create date
01/09/2011 12:13
Last modification date
20/08/2019 14:06
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