Hypoglycémie et traitement du diabète de type 2. Le retour à une normoglycémie n'est pas nécessairement la meilleure stratégie thérapeutique [Hypoglycemia and diabetes treatment: the return to normal glucose level is not always the best therapeutic strategy].

Details

Serval ID
serval:BIB_4FFECE129902
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hypoglycémie et traitement du diabète de type 2. Le retour à une normoglycémie n'est pas nécessairement la meilleure stratégie thérapeutique [Hypoglycemia and diabetes treatment: the return to normal glucose level is not always the best therapeutic strategy].
Journal
Revue Médicale Suisse
Author(s)
Ruiz J.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2013
Volume
9
Number
389
Pages
1182-1185
Language
french
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish. pdf type: perspective
Abstract
Recent clinical trials with type 2 diabetic patients and the quest of normal glyceamic values, have revealed difficulties and limitations. These too normal glyceamic targets corresponding to the physiological standards are associated with very high rate of hypoglycemia and an increase of mortality. A too simplistic view of treatment: "the lowest, the better is in the diabetes" is no longer defensible. The knowledge from complex systems behavior invites us to search targets adapted to a new state of equilibrium due to loss of self-regulation. These targets should not aim the physiological standards but to be adapted to patient's situation. Shared decision-making and consensus are the two pillars of this new strategy supported by the new ADA-EASD guidelines.
Keywords
Blood Glucose/analysis, Blood Glucose/physiology, Diabetes Mellitus, Type 2/blood, Diabetes Mellitus, Type 2/drug therapy, Humans, Hypoglycemia/blood, Hypoglycemia/physiopathology, Reference Standards, Standard of Care
Pubmed
Create date
19/09/2013 20:24
Last modification date
20/08/2019 14:05
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