Genome-wide expression patterns and the genetic architecture of a fundamental social trait.

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Serval ID
serval:BIB_4EA4893DF81F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Genome-wide expression patterns and the genetic architecture of a fundamental social trait.
Journal
PLoS Genetics
Author(s)
Wang J., Ross K.G., Keller L.
ISSN
1553-7404
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
4
Number
7
Pages
e1000127
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
Explaining how interactions between genes and the environment influence social behavior is a fundamental research goal, yet there is limited relevant information for species exhibiting natural variation in social organization. The fire ant Solenopsis invicta is characterized by a remarkable form of social polymorphism, with the presence of one or several queens per colony and the expression of other phenotypic and behavioral differences being completely associated with allelic variation at a single Mendelian factor marked by the gene Gp-9. Microarray analyses of adult workers revealed that differences in the Gp-9 genotype are associated with the differential expression of an unexpectedly small number of genes, many of which have predicted functions, implying a role in chemical communication relevant to the regulation of colony queen number. Even more surprisingly, worker gene expression profiles are more strongly influenced by indirect effects associated with the Gp-9 genotypic composition within their colony than by the direct effect of their own Gp-9 genotype. This constitutes an unusual example of an "extended phenotype" and suggests a complex genetic architecture with a single Mendelian factor, directly and indirectly influencing the individual behaviors that, in aggregate, produce an emergent colony-level phenotype.
Keywords
Alleles, Animals, Ants, Gene Expression Profiling, Gene Expression Regulation, Genes, Insect, Genetic Variation, Genotype, Haplotypes, Heterozygote, Homozygote, Insect Proteins, Oligonucleotide Array Sequence Analysis, Social Behavior
Pubmed
Web of science
Open Access
Yes
Create date
10/06/2008 20:19
Last modification date
20/08/2019 14:04
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