First Steps Towards a Risk of Bias Corpus of Randomized Controlled Trials
Details
Download: 37203753.pdf (245.73 [Ko])
State: Public
Version: Final published version
License: CC BY-NC 4.0
State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_4E63D97F7A1D
Type
A part of a book
Publication sub-type
Chapter: chapter ou part
Collection
Publications
Institution
Title
First Steps Towards a Risk of Bias Corpus of Randomized Controlled Trials
Title of the book
Caring is Sharing – Exploiting the Value in Data for Health and Innovation
Publisher
IOS Press
ISBN
9781643683881
9781643683898
9781643683898
ISSN
0926-9630
1879-8365
1879-8365
ISSN-L
0926-9630
Publication state
Published
Issued date
18/05/2023
Peer-reviewed
Oui
Volume
302
Series
Studies in Health Technology and Informatics
Pages
586-590.
Language
english
Abstract
Risk of bias (RoB) assessment of randomized clinical trials (RCTs) is vital to conducting systematic reviews. Manual RoB assessment for hundreds of RCTs is a cognitively demanding, lengthy process and is prone to subjective judgment. Supervised machine learning (ML) can help to accelerate this process but requires a hand-labelled corpus. There are currently no RoB annotation guidelines for randomized clinical trials or annotated corpora. In this pilot project, we test the practicality of directly using the revised Cochrane RoB 2.0 guidelines for developing an RoB annotated corpus using a novel multi-level annotation scheme. We report inter-annotator agreement among four annotators who used Cochrane RoB 2.0 guidelines. The agreement ranges between 0% for some bias classes and 76% for others. Finally, we discuss the shortcomings of this direct translation of annotation guidelines and scheme and suggest approaches to improve them to obtain an RoB annotated corpus suitable for ML.
Pubmed
Web of science
Open Access
Yes
Create date
24/05/2023 8:12
Last modification date
05/09/2024 9:00