Bilateral sequential optic neuropathy as the initial manifestation of Sjögren syndrome.

Details

Serval ID
serval:BIB_4CC6F6EFC0F6
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Bilateral sequential optic neuropathy as the initial manifestation of Sjögren syndrome.
Journal
Klinische Monatsblätter für Augenheilkunde
Author(s)
Pournaras J.A., Vaudaux J.D., Borruat F.X.
ISSN
0023-2165 (Print)
ISSN-L
0023-2165
Publication state
Published
Issued date
04/2007
Peer-reviewed
Oui
Volume
224
Number
4
Pages
337-339
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
BACKGROUND: Neuro-ophthalmic findings are uncommon in the setting of Sjögren syndrome. We report the case of a patient with bilateral, sequential optic neuropathy as the initial manifestation of Sjögren syndrome.
HISTORY AND SIGNS: A 38-year-old male presented with sudden painless visual loss in his left eye in May 2005. Fundus examination revealed a left swollen optic disk. Magnetic resonance imaging (MRI) revealed a left optic nerve lesion. Elevated titres of autoantibodies (ANA, anti-SSA, anti-SSB) were found, suggestive of Sjögren syndrome. In January 2006, he presented with painful sudden visual loss in the right eye. Fundus examination revealed a right swollen optic disk and left optic nerve atrophy. MRI was normal. Other aetiologies were ruled out.
THERAPY AND OUTCOME: Each episode was treated with intravenous methylprednisolone (1 g/day during 3 days), followed by oral prednisone (1 mg/kg/day). Moderate improvement of vision ensued in both eyes.
CONCLUSIONS: Atypical presentation of an optic neuropathy must raise the suspicion of an unusual aetiology. Our case illustrates how a bilateral sequential optic neuropathy in an otherwise healthy patient can result from an unusual inflammatory aetiology: primary Sjögren syndrome.
Keywords
Adult, Anti-Inflammatory Agents/administration & dosage, Drug Combinations, Humans, Male, Methylprednisolone/administration & dosage, Optic Nerve Diseases/diagnosis, Optic Nerve Diseases/drug therapy, Prednisone/administration & dosage, Sjogren's Syndrome/complications, Sjogren's Syndrome/diagnosis, Treatment Outcome
Pubmed
Web of science
Create date
28/01/2008 12:37
Last modification date
20/08/2019 14:01
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