Experimental bacterial endocarditis after dental extractions in rats with periodontitis.

Details

Ressource 1Download: serval:BIB_46F405BB0C65.P001 (548.33 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_46F405BB0C65
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Experimental bacterial endocarditis after dental extractions in rats with periodontitis.
Journal
Journal of Infectious Diseases
Author(s)
Overholser C.D., Moreillon P., Glauser M.P.
ISSN
0022-1899 (Print)
ISSN-L
0022-1899
Publication state
Published
Issued date
1987
Volume
155
Number
1
Pages
107-112
Language
english
Abstract
The development of bacterial endocarditis was analyzed after dental extractions in rats with or without periodontal disease. Periodontal disease was produced in rats by tying silk ligatures around the two maxillary first molars and placing the animals on a high sucrose diet for 14 weeks. Sterile aortic valve vegetations were produced by means of a transaortic catheter, and 24 hr later the maxillary first molars were extracted. The animals were killed 72 hr after the extractions. In rats with periodontal disease, extractions resulted in a 48% (14 of 29) incidence of bacterial endocarditis, most cases of which were due to Streptococcus spp. (one was caused by Staphylococcus aureus). In contrast, when the teeth with a healthy periodontium were extracted, only 6% (one of 15) of the rats developed endocarditis. When catheters were placed in animals with periodontal disease but no extractions were performed, no endocarditis occurred.
Keywords
Animals, Aortic Valve, Disease Models, Animal, Endocarditis, Bacterial/etiology, Female, Heart Catheterization, Periodontitis/complications, Rats, Rats, Inbred Strains, Staphylococcal Infections/etiology, Streptococcal Infections/etiology, Tooth Extraction/adverse effects
Pubmed
Open Access
Yes
Create date
24/01/2008 14:58
Last modification date
01/10/2019 7:17
Usage data