Muscle VO2 and forearm blood flow repeatability during venous and arterial occlusions in healthy and coronary heart disease subjects

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Serval ID
serval:BIB_46E6417DD9AB
Type
Article: article from journal or magazin.
Collection
Publications
Title
Muscle VO2 and forearm blood flow repeatability during venous and arterial occlusions in healthy and coronary heart disease subjects
Journal
Clin Hemorheol Microcirc
Author(s)
Gayda M., Gremeaux V., Drigny J., Juneau M., Nigam A.
ISSN
1875-8622 (Electronic)
ISSN-L
1386-0291
Publication state
Published
Issued date
2015
Volume
59
Number
2
Pages
177-83
Language
english
Notes
Gayda, Mathieu
Gremeaux, Vincent
Drigny, Joffrey
Juneau, Martin
Nigam, Anil
eng
Research Support, Non-U.S. Gov't
Netherlands
Clin Hemorheol Microcirc. 2015;59(2):177-83. doi: 10.3233/CH-141836.
Abstract
This study aims were: 1) to assess forearm blood flow (FBF) and muscle oxygen consumption (mVO2) repeatability assessed with near-infra red spectroscopy (NIRS) during venous occlusions (VO) in middle aged healthy subjects and patients with stable coronary heart disease (CHD), 2) to assess the agreement between mVO2 calculated from NIRS signals during VO and arterial occlusion (AO) in 18 middle aged healthy subjects and 12 patients with CHD. FBF and mVO2 were measured using NIRS during 2 successive VO (1-min duration), followed by a 5-min AO. Repeatability for FBF and mVO2 during VO was assessed with intra class correlation (ICC), coefficient of variation (CV %) and agreement between VO and AO mVO2 was assessed with a Bland and Altman analysis. FBF and mVO2 during VO were highly reproducible in healthy (FBF: ICC 0.73, CV% 9.75; mVO2: ICC 0.89, CV% 12.6) and CHD subjects (FBF: ICC 0.95, CV% 10.26; mVO2: ICC 0.98, CV% 7.92). VO and AO mVO2 were in agreement in healthy (mean bias: 0.002 mL O2.min-1.100g-1) and CHD subjects (mean bias: 0.014 mL O2.min-1.100g-1). FBF and mVO2 measured with NIRS during VO and/or AO are highly reproducible methods to assess microvascular function in healthy subjects and stable CHD patients.
Keywords
Coronary Disease/*genetics, Female, Forearm/*blood supply, Hemodynamics/*physiology, Humans, Male, Middle Aged, Oxygen Consumption/physiology, Regional Blood Flow/*physiology, Near-infra red spectroscopy, agreement, healthy middle aged subjects, patients with coronary heart disease, repeatability, vascular occlusions
Pubmed
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26/11/2019 12:35
Last modification date
04/05/2020 7:06
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