Zavisimost' mezhdy vnutrikletochnym soderzhaniem 1-metil-3-izobutilksantina i pronitsaemost'iu dlia vody stenki mochevogo puzyria liagushki [The relationship between the intracellular content of 1-methyl-3-isobutylxanthine and the permeability for water of the bladder wall in the frog].
Details
Serval ID
serval:BIB_4263AD2F0132
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Zavisimost' mezhdy vnutrikletochnym soderzhaniem 1-metil-3-izobutilksantina i pronitsaemost'iu dlia vody stenki mochevogo puzyria liagushki [The relationship between the intracellular content of 1-methyl-3-isobutylxanthine and the permeability for water of the bladder wall in the frog].
Journal
Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova
ISSN
0015-329X (Print)
ISSN-L
0015-329X
Publication state
Published
Issued date
1989
Volume
75
Number
12
Pages
1766-1771
Language
russian
Notes
Publication types: Comparative Study ; English Abstract ; Journal Article Publication Status: ppublish
Abstract
The data obtained show a direct interrelationship between the concentration of MIBX in cells and an increase of osmotic permeability. The method of determination of intracellular concentration of the MIBX using [3H]-MIBX, was developed, and the way to obtain radioactive MIBX described. The used approach permits to take into consideration functional changes as related to the intracellular concentration of inhibiting agents.
Keywords
1-Methyl-3-isobutylxanthine/pharmacology, 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors, Animals, Cell Membrane Permeability/drug effects, Cell Membrane Permeability/physiology, Cyclic AMP/pharmacology, Dose-Response Relationship, Drug, Osmosis/drug effects, Rana temporaria, Theophylline/analogs & derivatives, Tritium/diagnostic use, Urinary Bladder/drug effects, Urinary Bladder/physiology, Water/metabolism
Pubmed
Create date
24/01/2008 13:32
Last modification date
20/08/2019 14:44
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