Le traitement du glaucome a pression normale avec un antagoniste des recepteurs S2 de la serotonine, le naftidrofuryl (praxilen). [Treatment of normal pressure glaucoma with a serotonin S2 receptor antagonist, naftidrofuryl (praxilen)]

Details

Serval ID
serval:BIB_3B68615ADDFF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Le traitement du glaucome a pression normale avec un antagoniste des recepteurs S2 de la serotonine, le naftidrofuryl (praxilen). [Treatment of normal pressure glaucoma with a serotonin S2 receptor antagonist, naftidrofuryl (praxilen)]
Journal
Klinische Monatsblatter fur Augenheilkunde
Author(s)
Mermoud  A., Faggioni  R.
ISSN
0023-2165 (Print)
Publication state
Published
Issued date
05/1991
Volume
198
Number
5
Pages
332-4
Notes
Clinical Trial
Controlled Clinical Trial
English Abstract
Journal Article --- Old month value: May
Abstract
35 normal tension glaucoma patients were followed during 8 to 11 month. 12 patients received 2 x 200 mg/day Naftidrofuryl, a serotonine S2 receptor antagonist. As controles, another 23 patients were followed without treatment. The treated group, compared with the 23 non treated patients showed a significant increase in visual acuity (p = 0.001), a significant increase of the MS (p = 0.03), and a non significant decrease of the MD and CLV on the Octopus visual field (p, NS). The physiology and physiopathology of serotonine and S2 receptor antagonist are discussed.
Keywords
Aged Dose-Response Relationship, Drug Female Follow-Up Studies Glaucoma/*drug therapy Humans Intraocular Pressure/*drug effects Male Nafronyl/*administration & dosage Ophthalmic Solutions Pilot Projects *Serotonin Antagonists Visual Acuity/drug effects Visual Fields/drug effects
Pubmed
Web of science
Create date
28/01/2008 12:49
Last modification date
20/08/2019 13:31
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