Novel biomarkers to predict response and prognosis in localized bladder cancer.

Details

Serval ID
serval:BIB_3B4A681FC901
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Novel biomarkers to predict response and prognosis in localized bladder cancer.
Journal
Urologic Clinics of North America
Author(s)
Lucca I., de Martino M., Klatte T., Shariat S.F.
ISSN
1558-318X (Electronic)
ISSN-L
0094-0143
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
42
Number
2
Pages
225-33, ix
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review Publication Status: ppublishDocument Type: Review
Abstract
This review summarizes recent developments in diagnostic and prognostic biomarkers for nonmuscle invasive bladder cancer (NMIBC). Although the number of new biomarkers increases continuously, none are included in practice guidelines. Most NMIBC biomarkers show a higher sensitivity than urinary cytology, but lower specificity. Some protein and chromosome markers have been approved for screening and follow-up of patients in combination with cystoscopy. The long interval required for validation, testing, and approval of the assays and the lack of standardization could explain present issues in biomarker research. To enhance the development of new biomarkers, a more structured approach is required.
Pubmed
Web of science
Create date
12/06/2015 16:43
Last modification date
20/08/2019 13:31
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