Nicotine Replacement Therapy during Pregnancy and Child Health Outcomes: A Systematic Review.

Details

Serval ID
serval:BIB_360E84841B82
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Nicotine Replacement Therapy during Pregnancy and Child Health Outcomes: A Systematic Review.
Journal
International journal of environmental research and public health
Author(s)
Blanc J., Tosello B., Ekblad M.O., Berlin I., Netter A.
ISSN
1660-4601 (Electronic)
ISSN-L
1660-4601
Publication state
Published
Issued date
11/04/2021
Peer-reviewed
Oui
Volume
18
Number
8
Pages
4004
Language
english
Notes
Publication types: Journal Article ; Review ; Systematic Review
Publication Status: epublish
Abstract
Tobacco smoking in pregnancy is a worldwide public health problem. A majority of pregnant smokers need assistance to stop smoking. Most scientific societies recommend nicotine replacement therapy (NRT) during pregnancy but this recommendation remains controversial because of the known fetal toxicity of nicotine. The objective of this systematic review was to provide an overview of human studies about child health outcomes associated with NRT use during pregnancy. The electronic databases MEDLINE, the Cochrane Database, Web of Science, and ClinicalTrials.gov were searched from the inception of each database until 26 December 2020. A total of 103 articles were identified through database searching using combination of keywords. Out of 75 screened articles and after removal of duplicates, ten full-text articles were assessed for eligibility and five were included in the qualitative synthesis. NRT prescription seems to be associated with higher risk of infantile colic at 6 months as in case of smoking during pregnancy, and with risk of attention-deficit/hyperactivity disorder. No association between NRT during pregnancy and other infant health disorders or major congenital anomalies has been reported. Well-designed controlled clinical trials with sufficient follows-up are needed to provide more information on the use of NRT or other pharmacotherapies for smoking cessation during pregnancy on post-natal child health outcomes.
Keywords
Child, Child Health, Female, Humans, Nicotine, Pregnancy, Smoking, Smoking Cessation, Tobacco Use Cessation Devices, attention deficit disorder with hyperactivity, child health, congenital abnormalities, pregnancy, respiration disorders, smoking cessation agents, tobacco use cessation devices
Pubmed
Web of science
Open Access
Yes
Create date
19/05/2021 12:51
Last modification date
30/12/2023 7:07
Usage data