Ultrastructural changes of the internal limiting membrane (ILM) follow- ing intraretinal haemorrhage

Details

Serval ID
serval:BIB_3338AE46C387
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Title
Ultrastructural changes of the internal limiting membrane (ILM) follow- ing intraretinal haemorrhage
Title of the conference
Ophta 2011
Author(s)
Konstantinidis Lazaros, Stappler  Theodor (co-last)
Organization
104e Congrès annuel de la Société Suisse d’Ophtalmologie
Address
Casino Kursaal Interlaken AG,
Strandbadstrasse 44,
CH-3800 Interlaken
Publication state
Published
Issued date
03/09/2011
Peer-reviewed
Oui
Pages
S48
Language
english
Abstract
Intraretinal hemorrhage is a relatively common clinical manifestation associated with various aetiologies. Our knowledge is, however, very limited regarding the ultrastructural changes that they can generate on the retina and the clinical significance thereof. Patients and Methods Clinicopathologic study of patients presenting sub-ILM macular hemorrhages for various aetiologies. All patients underwent pars plana vitrectomy associated with ILM peel. Results The study included 5 patients with Terson’s Syndrome, 2 cases of ruptured macroaneurysms and 3 cases of Valsalva retin- opathy. Cellular proliferations identified on the retinal surface of the excised ILM in 6 specimens that included transdifferentiated RPE cells, glial cells and macrophages simulating a proliferative vitreoretinopathy (PVR)-type response. The cellular proliferation was positively correlated to the delay of the surgery while visual recovery was inversely correlated to the delay of the surgery. Con- clusions Cellular proliferation, similar to that seen in PVR epireti- nal membranes occurs within the neuroretina after haemorrhage, specifically beneath the ILM. This might prevent complete visual recovery after haemorrhage re-absorption and could justify early surgical intervention.
Keywords
Retina
Create date
06/09/2019 10:05
Last modification date
07/09/2019 5:26
Usage data