Membrane fluidization triggers membrane remodeling which affects the thermotolerance in Escherichia coli.

Details

Serval ID
serval:BIB_31EEB8836942
Type
Article: article from journal or magazin.
Collection
Publications
Title
Membrane fluidization triggers membrane remodeling which affects the thermotolerance in Escherichia coli.
Journal
Biochemical and Biophysical Research Communications
Author(s)
Shigapova N., Török Z., Balogh G., Goloubinoff P., Vígh L., Horváth I.
ISSN
0006-291X (Print)
ISSN-L
0006-291X
Publication state
Published
Issued date
2005
Volume
328
Number
4
Pages
1216-1223
Language
english
Abstract
Treatment of Escherichia coli with non-lethal doses of heat or benzyl alcohol (BA) causes transient membrane fluidization and permeabilization, and induces the rapid transcription of heat-shock genes in a sigma32-dependent manner. This early response is followed by a rapid adaptation (priming) of the cells to otherwise lethal elevated temperature, in strong correlation with an observed remodeling of the composition and alkyl chain unsaturation of membrane lipids. The acquisition of cellular thermotolerance in BA-primed cells is unrelated to protein denaturation and is not accompanied by the formation of major heat-shock proteins, such as GroEL and DnaK. This suggests that the rapid remodeling of membrane composition is sufficient for the short-term bacterial thermotolerance.
Keywords
Adaptation, Physiological/drug effects, Adaptation, Physiological/physiology, Benzyl Alcohol/pharmacology, Cell Membrane Permeability/drug effects, Cell Membrane Permeability/physiology, Dose-Response Relationship, Drug, Dose-Response Relationship, Radiation, Escherichia coli/drug effects, Escherichia coli/physiology, Heat-Shock Response/drug effects, Heat-Shock Response/physiology, Hot Temperature, Membrane Fluidity/drug effects, Membrane Fluidity/physiology
Pubmed
Web of science
Create date
24/01/2008 21:02
Last modification date
20/08/2019 14:17
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