Assessment of the Role of 1,3-β-d-Glucan Testing for the Diagnosis of Invasive Fungal Infections in Adults.

Details

Serval ID
serval:BIB_309237C62F3D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Assessment of the Role of 1,3-β-d-Glucan Testing for the Diagnosis of Invasive Fungal Infections in Adults.
Journal
Clinical infectious diseases
Author(s)
Lamoth F., Akan H., Andes D., Cruciani M., Marchetti O., Ostrosky-Zeichner L., Racil Z., Clancy C.J.
ISSN
1537-6591 (Electronic)
ISSN-L
1058-4838
Publication state
Published
Issued date
12/03/2021
Peer-reviewed
Oui
Volume
72
Number
Suppl 2
Pages
S102-S108
Language
english
Notes
Publication types: Journal Article ; Systematic Review
Publication Status: ppublish
Abstract
Detection of 1,3-β-d-glucan (BDG) in serum has been evaluated for its inclusion as a mycological criterion of invasive fungal infections (IFI) according to EORTC and Mycoses Study Group (MSG) definitions. BDG testing may be useful for the diagnosis of both invasive aspergillosis and invasive candidiasis, when interpreted in conjunction with other clinical/radiological signs and microbiological markers of IFI. However, its performance and utility vary according to patient population (hematologic cancer patients, solid-organ transplant recipients, intensive care unit patients) and pretest likelihood of IFI. The objectives of this article are to provide a systematic review of the performance of BDG testing and to assess recommendations for its use and interpretation in different clinical settings.
Keywords
Adult, Candidiasis, Invasive/diagnosis, Glucans, Humans, Invasive Fungal Infections/diagnosis, Sensitivity and Specificity, beta-Glucans, beta-glucan, hematologic cancer, intensive care, invasive aspergillosis, invasive candidiasis
Pubmed
Web of science
Open Access
Yes
Create date
17/03/2021 16:08
Last modification date
08/05/2021 5:32
Usage data