Assessment of the Role of 1,3-β-d-Glucan Testing for the Diagnosis of Invasive Fungal Infections in Adults.

Détails

ID Serval
serval:BIB_309237C62F3D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Assessment of the Role of 1,3-β-d-Glucan Testing for the Diagnosis of Invasive Fungal Infections in Adults.
Périodique
Clinical infectious diseases
Auteur(s)
Lamoth F., Akan H., Andes D., Cruciani M., Marchetti O., Ostrosky-Zeichner L., Racil Z., Clancy C.J.
ISSN
1537-6591 (Electronic)
ISSN-L
1058-4838
Statut éditorial
Publié
Date de publication
12/03/2021
Peer-reviewed
Oui
Volume
72
Numéro
Suppl 2
Pages
S102-S108
Langue
anglais
Notes
Publication types: Journal Article ; Systematic Review
Publication Status: ppublish
Résumé
Detection of 1,3-β-d-glucan (BDG) in serum has been evaluated for its inclusion as a mycological criterion of invasive fungal infections (IFI) according to EORTC and Mycoses Study Group (MSG) definitions. BDG testing may be useful for the diagnosis of both invasive aspergillosis and invasive candidiasis, when interpreted in conjunction with other clinical/radiological signs and microbiological markers of IFI. However, its performance and utility vary according to patient population (hematologic cancer patients, solid-organ transplant recipients, intensive care unit patients) and pretest likelihood of IFI. The objectives of this article are to provide a systematic review of the performance of BDG testing and to assess recommendations for its use and interpretation in different clinical settings.
Mots-clé
Adult, Candidiasis, Invasive/diagnosis, Glucans, Humans, Invasive Fungal Infections/diagnosis, Sensitivity and Specificity, beta-Glucans, beta-glucan, hematologic cancer, intensive care, invasive aspergillosis, invasive candidiasis
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/03/2021 17:08
Dernière modification de la notice
08/05/2021 6:32
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