Amyloïdose cardiaque: une maladie rare ? [Cardiac amyloidosis : a rare disease ?]

Details

Serval ID
serval:BIB_2F7A12565706
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Amyloïdose cardiaque: une maladie rare ? [Cardiac amyloidosis : a rare disease ?]
Journal
Revue medicale suisse
Author(s)
Hugelshofer S., N'koulou R., Monney P.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
22/05/2019
Peer-reviewed
Oui
Volume
15
Number
652
Pages
1054-1059
Language
french
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Cardiac amyloidosis is an infiltrative cardiomyopathy, typically conducting to heart failure with preserved ejection fraction. There are several causes for the disease, from which two can already be seen in the young patient and are due to either genetic mutation or neoplasia. A third, non genetic cause, typically affects older patients (previously called senile amyloidosis) and appears to be much more prevalent than initially reported. A careful initial work-up and a high index of suspicion are important to detect as early as possible the disease, as it is associated with a poor prognosis in the late stage. A standardized diagnostic approach has been proposed with the use of bone scintigraphy, recently recognized as a sensitive diagnostic tool for this type of amyloidosis. With new disease modifying therapies recently becoming available, a more active diagnostic strategy is justified.
Keywords
Amyloidosis/diagnosis, Cardiomyopathies/diagnosis, Heart Failure, Humans, Rare Diseases
Pubmed
Create date
25/05/2019 10:21
Last modification date
20/08/2019 13:13
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