Characteristics of uterine contractility during menses in women with mild to moderate endometriosis

Details

Serval ID
serval:BIB_2C0D96678F73
Type
Article: article from journal or magazin.
Collection
Publications
Title
Characteristics of uterine contractility during menses in women with mild to moderate endometriosis
Journal
Fertility and Sterility
Author(s)
Bulletti  C., De Ziegler  D., Polli  V., Del Ferro  E., Palini  S., Flamigni  C.
ISSN
0015-0282
Publication state
Published
Issued date
06/2002
Peer-reviewed
Oui
Volume
77
Number
6
Pages
1156-61
Notes
Journal Article --- Old month value: Jun
Abstract
OBJECTIVE: To establish the role of uterine contractions in retrograde menstruation with subsequent abdominal implantation of endometrial tissue. DESIGN: Controlled prospective study. SETTING: University hospital-based study. PATIENT(S): Infertile women with (n = 22) and without (n = 22) endometriosis. MAIN OUTCOME MEASURE(S): Frequency, amplitude, and basal pressure tone of uterine contractions; correlation of contractions with retrograde bleeding and presence of viable endometrial cells; and dysmenorrhea before and 3 and 24 months after surgery. RESULT(S): Compared with controls, patients with endometriosis had uterine contractions with higher frequency (22.73 +/- 5.66 osc/10 min vs. 11.09 +/- 3.26 osc/10 min), amplitude (20.83 +/- 3.94 mm Hg vs. 6.77 +/- 2.83 mm Hg), and basal pressure tone (50.14 +/- 16.30 mm Hg vs. 24.68 +/- 6.14 mm Hg). Dysmenorrhea was scored as 4.09 +/- 1.44 in patients with endometriosis and 0.86 +/- 1.42 in controls. Retrograde bleeding was found in 73% of patients with endometriosis vs. 9% of controls, and only 45% of patients with endometriosis had viable endometrial cells in the cul-de-sac. CONCLUSION(S): Endometriosis may result from abnormal myometrial contractility through tubal transportation, dissemination, and implantation of endometrial viable cells into the abdomen.
Keywords
Adult Dysmenorrhea/epidemiology/etiology Endometriosis/complications/pathology/*physiopathology Endometrium/pathology Female Humans Incidence Menstruation/*physiology Severity of Illness Index Uterine Contraction/*physiology Uterine Hemorrhage/etiology
Pubmed
Web of science
Create date
28/02/2008 11:37
Last modification date
20/08/2019 13:11
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