Prevention of microalbuminuria in patients with type 2 diabetes: what do we know?

Details

Serval ID
serval:BIB_27E87C77598B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Prevention of microalbuminuria in patients with type 2 diabetes: what do we know?
Journal
Journal of Clinical Hypertension
Author(s)
Ruilope Luis, Izzo Joseph, Haller Hermann, Waeber Bernard, Oparil Suzanne, Weber Michael, Bakris George, Sowers James
ISSN
1751-7176[electronic], 1524-6175[linking]
Publication state
Published
Issued date
2010
Volume
12
Number
6
Pages
422-430
Language
english
Abstract
Cardiovascular and chronic kidney disease are epidemic throughout industrialized societies. Diabetes leads to premature cardiovascular disease and is regarded by many as the most common etiological factor for chronic kidney disease. Because most studies of blood-pressure lowering agents in people with diabetes and hypertension have been conducted in individuals who already have some target organ damage, it is unclear whether earlier intervention could prevent or delay the onset of renal or systemic vascular disease. In early disease there is only a low possibility of observing cardiovascular or renal events; thus intervention trials in this population must rely on disease markers such as microalbuminuria. Accordingly, the authors review the evidence to support the use of microalbuminuria as a disease marker in diabetic patients based on its strong association with renal and cardiovascular events, and discuss recent trials that examine the impact of preventing or delaying the onset of microalbuminuria.
Keywords
Society-of-Hypertension, Chronic Kidney-Disease, Growth-Factor Vegf, Blood-Pressure, Angiotensin-Receptor, High-Risk, Endothelial Dysfunction, Cardiovascular Events, Consensus Statement, Randomized-Trials
Pubmed
Web of science
Create date
19/07/2010 14:47
Last modification date
20/08/2019 13:07
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