Prevention of microalbuminuria in patients with type 2 diabetes: what do we know?

Détails

ID Serval
serval:BIB_27E87C77598B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Prevention of microalbuminuria in patients with type 2 diabetes: what do we know?
Périodique
Journal of Clinical Hypertension
Auteur⸱e⸱s
Ruilope Luis, Izzo Joseph, Haller Hermann, Waeber Bernard, Oparil Suzanne, Weber Michael, Bakris George, Sowers James
ISSN
1751-7176[electronic], 1524-6175[linking]
Statut éditorial
Publié
Date de publication
2010
Volume
12
Numéro
6
Pages
422-430
Langue
anglais
Résumé
Cardiovascular and chronic kidney disease are epidemic throughout industrialized societies. Diabetes leads to premature cardiovascular disease and is regarded by many as the most common etiological factor for chronic kidney disease. Because most studies of blood-pressure lowering agents in people with diabetes and hypertension have been conducted in individuals who already have some target organ damage, it is unclear whether earlier intervention could prevent or delay the onset of renal or systemic vascular disease. In early disease there is only a low possibility of observing cardiovascular or renal events; thus intervention trials in this population must rely on disease markers such as microalbuminuria. Accordingly, the authors review the evidence to support the use of microalbuminuria as a disease marker in diabetic patients based on its strong association with renal and cardiovascular events, and discuss recent trials that examine the impact of preventing or delaying the onset of microalbuminuria.
Mots-clé
Society-of-Hypertension, Chronic Kidney-Disease, Growth-Factor Vegf, Blood-Pressure, Angiotensin-Receptor, High-Risk, Endothelial Dysfunction, Cardiovascular Events, Consensus Statement, Randomized-Trials
Pubmed
Web of science
Création de la notice
19/07/2010 14:47
Dernière modification de la notice
20/08/2019 13:07
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