Frosted branch angiitis with undiagnosed Hodgkin lymphoma.
Details
Serval ID
serval:BIB_262BAD2D27CA
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Frosted branch angiitis with undiagnosed Hodgkin lymphoma.
Journal
European Journal of Ophthalmology
ISSN
1120-6721[print], 1120-6721[linking]
Publication state
Published
Issued date
2009
Volume
19
Number
2
Pages
310-313
Language
english
Abstract
PURPOSE: To report the case of a patient with bilateral frosted branch angiitis and undiagnosed Hodgkin lymphoma. METHODS: Review of clinical history, laboratory findings, histology of supraclavicular lymph node biopsy, and follow-up. RESULTS: A 22-year-old man presented with a sudden, bilateral visual loss. Fundus examination and fluorescein angiography disclosed a bilateral frosted branch angiitis that was dramatically responsive to systemic corticosteroid therapy. Laboratory tests were unremarkable but radiologic studies showed extensive mediastinal and supraclavicular lymphadenopathy. A supraclavicular lymph node biopsy led to the diagnosis of nodular sclerosis Hodgkin lymphoma. CONCLUSIONS: The occurrence of frosted branch angiitis in combination with classical Hodgkin lymphoma, although possibly coincidental, raises the possibility of a paraneoplastic syndrome. Thus, we suggest that, for patients with frosted branch angiitis, Hodgkin lymphoma should be considered in the diagnostic workup.
Keywords
Administration, Oral, Biopsy, Fluorescein Angiography, Glucocorticoids/therapeutic use, Hodgkin Disease/diagnosis, Humans, Infusions, Intravenous, Lymph Nodes/pathology, Male, Methylprednisolone/therapeutic use, Retinal Vasculitis/diagnosis, Visual Acuity, Young Adult
Pubmed
Create date
22/10/2010 13:56
Last modification date
20/08/2019 13:04