MIMAS 3.0 is a Multiomics Information Management and Annotation System.

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Version: author
Serval ID
serval:BIB_2455DAB29335
Type
Article: article from journal or magazin.
Collection
Publications
Title
MIMAS 3.0 is a Multiomics Information Management and Annotation System.
Journal
BMC Bioinformatics
Author(s)
Gattiker A., Hermida L., Liechti R., Xenarios I., Collin O., Rougemont J., Primig M.
ISSN
1471-2105 (Electronic)
ISSN-L
1471-2105
Publication state
Published
Issued date
2009
Volume
10
Pages
151
Language
english
Abstract
BACKGROUND: DNA sequence integrity, mRNA concentrations and protein-DNA interactions have been subject to genome-wide analyses based on microarrays with ever increasing efficiency and reliability over the past fifteen years. However, very recently novel technologies for Ultra High-Throughput DNA Sequencing (UHTS) have been harnessed to study these phenomena with unprecedented precision. As a consequence, the extensive bioinformatics environment available for array data management, analysis, interpretation and publication must be extended to include these novel sequencing data types.
DESCRIPTION: MIMAS was originally conceived as a simple, convenient and local Microarray Information Management and Annotation System focused on GeneChips for expression profiling studies. MIMAS 3.0 enables users to manage data from high-density oligonucleotide SNP Chips, expression arrays (both 3'UTR and tiling) and promoter arrays, BeadArrays as well as UHTS data using MIAME-compliant standardized vocabulary. Importantly, researchers can export data in MAGE-TAB format and upload them to the EBI's ArrayExpress certified data repository using a one-step procedure.
CONCLUSION: We have vastly extended the capability of the system such that it processes the data output of six types of GeneChips (Affymetrix), two different BeadArrays for mRNA and miRNA (Illumina) and the Genome Analyzer (a popular Ultra-High Throughput DNA Sequencer, Illumina), without compromising on its flexibility and user-friendliness. MIMAS, appropriately renamed into Multiomics Information Management and Annotation System, is currently used by scientists working in approximately 50 academic laboratories and genomics platforms in Switzerland and France. MIMAS 3.0 is freely available via http://multiomics.sourceforge.net/.
Keywords
Abstracting and Indexing as Topic/methods, Database Management Systems, Databases, Genetic, Genomics/methods, Information Storage and Retrieval/methods, Internet, Oligonucleotide Array Sequence Analysis, Software
Pubmed
Web of science
Open Access
Yes
Create date
17/10/2012 12:05
Last modification date
20/08/2019 13:02
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