Magnetresonanz in der pädiatrischen Forschung und Klinik. II. Teil: Untersuchungen zur Entwicklung und Pathologie des Gehirns bei Neugeborenen, Säuglingen und Kleinkindern [Magnetic resonance in pediatric research and clinical practice. II. Studies on the development and pathology of the brain in neonates, infants and young children].

Details

Serval ID
serval:BIB_243819DCE53C
Type
Article: article from journal or magazin.
Collection
Publications
Title
Magnetresonanz in der pädiatrischen Forschung und Klinik. II. Teil: Untersuchungen zur Entwicklung und Pathologie des Gehirns bei Neugeborenen, Säuglingen und Kleinkindern [Magnetic resonance in pediatric research and clinical practice. II. Studies on the development and pathology of the brain in neonates, infants and young children].
Journal
Helvetica Paediatrica Acta
Author(s)
Martin E., Boesch C., Grütter R., Kikinis R., Kewitz G., Boltshauser E., Werner B., Eich G.
ISSN
0018-022X (Print)
ISSN-L
0018-022X
Publication state
Published
Issued date
1988
Volume
43
Number
1-2
Pages
75-86
Language
german
Notes
Publication types: English Abstract ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
We are investigating metabolism and morphological differentiation of the developing brain in neonates and children under non-invasive conditions combining MR imaging (MRI) with spectroscopy (MRS) on a high-field/small-bore (2.35 Tesla/40 cm) system. By the end of 1987, 116 neonates, infants and young children with various perinatal problems, congenital abnormalities and different neurological diseases have been examined with MRI. In addition, MRS studies were subsequently performed on 46 of these children using the same instrument and within the same session. The small, sometimes very sick and instable patients require careful monitoring and elaborate technical devices in the high magnetic field. We are presenting solutions for methodological and technical developments and adaptations, concepts for sedation and measurement protocols in various age groups and first results of the combined use of MRI and MRS to investigate the brain in neonates and infants.
Keywords
Brain/growth & development, Brain/metabolism, Central Nervous System Diseases/metabolism, Central Nervous System Diseases/pathology, Child, Preschool, Clinical Protocols, Humans, Infant, Infant, Newborn, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Myelin Sheath/physiology
Pubmed
Create date
29/04/2013 9:41
Last modification date
20/08/2019 13:02
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