Homolonto: generating homology relationships by pairwise alignment of ontologies and application to vertebrate anatomy.

Details

Ressource 1Download: BIB_1DA8753017CD.P001.pdf (144.28 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_1DA8753017CD
Type
Article: article from journal or magazin.
Collection
Publications
Title
Homolonto: generating homology relationships by pairwise alignment of ontologies and application to vertebrate anatomy.
Journal
Bioinformatics
Author(s)
Parmentier G., Bastian F.B., Robinson-Rechavi M.
ISSN
1367-4811[electronic], 1367-4803[linking]
Publication state
Published
Issued date
2010
Peer-reviewed
Oui
Volume
26
Number
14
Pages
1766-1771
Language
english
Abstract
MOTIVATION: The anatomy of model species is described in ontologies, which are used to standardize the annotations of experimental data, such as gene expression patterns. To compare such data between species, we need to establish relations between ontologies describing different species. RESULTS: We present a new algorithm, and its implementation in the software Homolonto, to create new relationships between anatomical ontologies, based on the homology concept. Homolonto uses a supervised ontology alignment approach. Several alignments can be merged, forming homology groups. We also present an algorithm to generate relationships between these homology groups. This has been used to build a multi-species ontology, for the database of gene expression evolution Bgee. AVAILABILITY: download section of the Bgee website http://bgee.unil.ch/
Pubmed
Web of science
Open Access
Yes
Create date
26/05/2010 13:52
Last modification date
20/08/2019 13:53
Usage data