Early ovarian cancer.

Details

Serval ID
serval:BIB_1CBA53296064
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Early ovarian cancer.
Journal
Current Treatment Options in Oncology
Author(s)
Coukos G., Rubin S.C.
ISSN
1527-2729 (Print)
ISSN-L
1534-6277
Publication state
Published
Issued date
2000
Volume
1
Number
2
Pages
129-137
Language
english
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublish
Abstract
Epithelial ovarian cancer may appear to be confined to the ovaries or pelvis in approximately one-third of patients at exploration, but up to 30% of them will be upstaged following surgical staging. Substage and histotype are the most important prognostic factors that determine the need for adjuvant treatment. Patients with stage Ia or Ib and well-differentiated (other than clear cell) tumors do not require adjuvant treatment. Patients with stage Ia or Ib grade 3 or clear cell histology, as well as any stage Ic and II disease, are at high risk for recurrence. Platinum-based chemotherapy is the mainstay of treatment. Four to six courses are probably adequate, although grade 3 tumors may require further treatment. Preservation of the uterus and the uninvolved contralateral ovary is a viable option in young women with unilateral early disease.
Keywords
Chemotherapy, Adjuvant, Female, Humans, Ovarian Neoplasms/mortality, Ovarian Neoplasms/pathology, Survival Rate, Urogenital Surgical Procedures
Pubmed
Create date
14/10/2014 11:42
Last modification date
20/08/2019 12:53
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