Early ovarian cancer.

Détails

ID Serval
serval:BIB_1CBA53296064
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Early ovarian cancer.
Périodique
Current Treatment Options in Oncology
Auteur⸱e⸱s
Coukos G., Rubin S.C.
ISSN
1527-2729 (Print)
ISSN-L
1534-6277
Statut éditorial
Publié
Date de publication
2000
Volume
1
Numéro
2
Pages
129-137
Langue
anglais
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublish
Résumé
Epithelial ovarian cancer may appear to be confined to the ovaries or pelvis in approximately one-third of patients at exploration, but up to 30% of them will be upstaged following surgical staging. Substage and histotype are the most important prognostic factors that determine the need for adjuvant treatment. Patients with stage Ia or Ib and well-differentiated (other than clear cell) tumors do not require adjuvant treatment. Patients with stage Ia or Ib grade 3 or clear cell histology, as well as any stage Ic and II disease, are at high risk for recurrence. Platinum-based chemotherapy is the mainstay of treatment. Four to six courses are probably adequate, although grade 3 tumors may require further treatment. Preservation of the uterus and the uninvolved contralateral ovary is a viable option in young women with unilateral early disease.
Mots-clé
Chemotherapy, Adjuvant, Female, Humans, Ovarian Neoplasms/mortality, Ovarian Neoplasms/pathology, Survival Rate, Urogenital Surgical Procedures
Pubmed
Création de la notice
14/10/2014 12:42
Dernière modification de la notice
20/08/2019 13:53
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