CD14 and LBP in endotoxemia and infections caused by Gram-negative bacteria.
Details
Serval ID
serval:BIB_19613
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
CD14 and LBP in endotoxemia and infections caused by Gram-negative bacteria.
Journal
Journal of Endotoxin Research
ISSN
0968-0519 (Print)
ISSN-L
0968-0519
Publication state
Published
Issued date
2001
Volume
7
Number
6
Pages
439-441
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
It is now well recognized that plasma LPS-binding protein (LBP) and membrane CD14 present at the surface of cells of the myelo/monocytic lineage are central molecules of the innate immune system, in response to LPS or to bacterial products. This paper reviews the role of LBP and CD14 in models of endotoxemia and infection.
Keywords
Acute-Phase Proteins, Animals, Antibodies, Monoclonal/therapeutic use, Antigens, CD14/genetics, Antigens, CD14/physiology, Carrier Proteins/genetics, Carrier Proteins/physiology, Disease Models, Animal, Endotoxemia/immunology, Endotoxemia/prevention & control, Gram-Negative Bacterial Infections/immunology, Membrane Glycoproteins, Mice, Mice, Knockout
OAI-PMH
Pubmed
Web of science
Create date
19/11/2007 13:14
Last modification date
20/08/2019 13:50
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