Coordinated polar localization of auxin efflux carrier PIN1 by GNOM ARF GEF.

Details

Serval ID
serval:BIB_0D4194B02FB8
Type
Article: article from journal or magazin.
Collection
Publications
Title
Coordinated polar localization of auxin efflux carrier PIN1 by GNOM ARF GEF.
Journal
Science
Author(s)
Steinmann T., Geldner N., Grebe M., Mangold S., Jackson C.L., Paris S., Gälweiler L., Palme K., Jürgens G.
ISSN
0036-8075 (Print)
ISSN-L
0036-8075
Publication state
Published
Issued date
1999
Volume
286
Number
5438
Pages
316-318
Language
english
Abstract
The plant hormone auxin is transported in a polar manner along the shoot-root axis, which requires efflux carriers such as PIN1. Asymmetric localization of PIN1 develops from a random distribution in Arabidopsis early embryogenesis. Coordinated polar localization of PIN1 is defective in gnom embryos. GNOM is a membrane-associated guanine-nucleotide exchange factor on ADP-ribosylation factor G protein (ARF GEF). Thus, GNOM-dependent vesicle trafficking may establish cell polarity, resulting in polar auxin transport.
Keywords
ADP-Ribosylation Factors/metabolism, Arabidopsis/cytology, Arabidopsis/embryology, Arabidopsis Proteins, Biological Transport, Brefeldin A/pharmacology, Cell Membrane/metabolism, Cell Polarity, Cytosol/metabolism, Guanine Nucleotide Exchange Factors/chemistry, Guanine Nucleotide Exchange Factors/genetics, Indoleacetic Acids/metabolism, Membrane Proteins/metabolism, Membrane Transport Proteins, Plant Roots/growth & development, Plant Roots/metabolism, Protein Conformation, Recombinant Proteins/metabolism, Seeds/cytology, Seeds/metabolism, Solubility, Subcellular Fractions/metabolism
Pubmed
Web of science
Create date
09/03/2008 18:19
Last modification date
20/08/2019 12:34
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