Genomic islands and the evolution of catabolic pathways in bacteria.

Details

Serval ID
serval:BIB_032E4BAFD3C5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Genomic islands and the evolution of catabolic pathways in bacteria.
Journal
Current Opinion in Biotechnology
Author(s)
van der Meer J.R., Sentchilo V.
ISSN
0958-1669 (Print)
ISSN-L
0958-1669
Publication state
Published
Issued date
2003
Volume
14
Number
3
Pages
248-254
Language
english
Abstract
Genes for the degradation of organic pollutants have usually been allocated to plasmid DNAs in bacteria or considered non-mobile when detected in the chromosome. New discoveries have shown that catabolic genes can also be part of so-called integrative and conjugative elements (ICElands), a group of mobile DNA elements also known as genomic islands and conjugative transposons. One such ICEland is the clc element for chlorobenzoate and chlorocatechol degradation in Pseudomonas sp. strain B13. Genome comparisons and genetic data on integrase functioning reveal that the clc element and several other unclassified ICElands belong to a group of elements with conserved features. The clc element is unique among them in carrying the genetic information for several degradation pathways, whereas the others give evidence for pathogenicity functions. Many more such elements may exist, bridging the gap between pathogenicity and degradation functions.
Keywords
Catalysis, DNA Transposable Elements, Energy Metabolism, Environmental Pollutants/metabolism, Evolution, Molecular, Gene Expression Regulation, Bacterial/physiology, Genes, Regulator, Genomic Islands/genetics, Pseudomonas/genetics, Pseudomonas/metabolism
Pubmed
Web of science
Create date
21/01/2008 14:36
Last modification date
20/08/2019 13:25
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