The metabolic effects of limbic leucotomy in Gilles de la Tourette syndrome.
Details
Serval ID
serval:BIB_02676AACEF5B
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
The metabolic effects of limbic leucotomy in Gilles de la Tourette syndrome.
Journal
Journal of Neurology, Neurosurgery, and Psychiatry
ISSN
0022-3050 (Print)
ISSN-L
0022-3050
Publication state
Published
Issued date
1993
Volume
56
Number
9
Pages
1016-1019
Language
english
Notes
Publication types: Case Reports ; Journal ArticlePublication Status: ppublish
Abstract
Regional cerebral oxygen metabolism was measured before and after limbic leucotomy in a patient with Gilles de la Tourette syndrome, obsessive compulsive disorder, and obsessional slowness. The preoperative scan showed hypermetabolism in the caudate nuclei, which normalised after operation. It is proposed that the beneficial effects of this operation on both tics and obsessive compulsive behaviour are mediated by disruption of abnormal neural activity in basal ganglia-thalamocortical loops.
Keywords
Brain/metabolism, Electrocoagulation, Humans, Limbic System/surgery, Male, Middle Aged, Oxygen/metabolism, Tomography, Emission-Computed, Tourette Syndrome/metabolism, Tourette Syndrome/surgery
Pubmed
Web of science
Open Access
Yes
Create date
22/09/2011 18:25
Last modification date
20/08/2019 13:24
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