Long term followup of photorefractive keratectomy with adjuvant use of mitomycin C.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_021744C22435
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long term followup of photorefractive keratectomy with adjuvant use of mitomycin C.
Journal
Journal of ophthalmology
Author(s)
Diakonis V.F., Kankariya V.P., Kymionis G.D., Kounis G., Kontadakis G., Gkenos E., Grentzelos M.A., Hajithanasis G., Yoo S.H., Pallikaris I.G.
ISSN
2090-004X (Print)
ISSN-L
2090-004X
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
2014
Pages
821920
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Purpose. To study the long term refractive and visual outcomes of photorefractive keratectomy (PRK) with intraoperative application of mitomycin C (MMC). Methods. This study included 37 eyes who received myopic PRK; after photoablation, a sponge soaked in 0.02% MMC solution was applied in all corneas for 2 minutes. Efficacy, safety, predictability, and stability of PRK MMC were evaluated. Endothelial cell density was evaluated at the last postoperative interval. Results. Mean preoperative spherical equivalent (SEQ) was -6.03 ± 1.87 D (diopters) and reduced to -0.09 ± 0.53 D at the last postoperative examination. Mean followup was 44.73 ± 18.24 months. All the eyes were in the ±1.00 D of attempted versus achieved SEQ at the one-year follow-up interval. Furthermore, 95% of the eyes did not lose lines or gained 1 to 2 lines of CDVA, while 5% lost 1 line. At the third postoperative month, 89% of the eyes either were clear or had trace haze, while 4 eyes had mild haze; by the 12-month postoperative interval, none of the eyes demonstrated haze. Mean endothelial cell density (ECD) at the last postoperative interval was 2658 ± 153 cells/mm(2). Conclusions. PRK, with intraoperative use of MMC, demonstrates stable refractive and visual outcomes up to 44 months after surgery.
Pubmed
Web of science
Open Access
Yes
Create date
30/09/2019 16:22
Last modification date
13/01/2021 7:08
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