serval:BIB_F2C1CC892374
Patients at risk of complications of Staphylococcus aureus bloodstream infection.
10.1086/598187
000265279600003
19374580
del Rio
A.
author
Cervera
C.
author
Moreno
A.
author
Moreillon
P.
author
MirĂ³
J.M.
author
article
review
2009
Clinical Infectious Diseases
1537-6591
1058-4838
journal
48 Suppl 4
S246-S253
Staphylococcus aureus is one of the most common causative pathogens of bloodstream infections (BSIs). In approximately one-half of patients with S. aureus BSI, no portal of entry can be documented. This group of patients has a high risk of developing septic metastases. Similarly, patient populations at high risk of S. aureus BSI and BSI-associated complications include patients receiving hemodialysis, injection drug users, patients with diabetes, and patients with preexisting cardiac conditions or other comorbidities. One of the most severe complications of S. aureus BSI is infective endocarditis, and S. aureus is now the most common cause of infective endocarditis in the developed world. Patients with methicillin-resistant S. aureus BSI or infective endocarditis have higher rates of mortality, compared with patients with methicillin-susceptible S. aureus infection. Nasal carriage is the most important source of S. aureus BSI. Better eradication and control strategies, including nasal decolonization and more-active antibiotics, are needed to combat S. aureus BSIs.
Bacteremia/complications
Bacteremia/drug therapy
Carrier State
Endocarditis/etiology
Humans
Methicillin-Resistant Staphylococcus aureus/isolation & purification
Nasal Cavity/microbiology
Risk Factors
Staphylococcal Infections/complications
Staphylococcal Infections/drug therapy
Staphylococcus aureus/isolation & purification
eng
60_published
true
University of Lausanne
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