serval:BIB_F1AD4B1D1680
Evidence of systematic and proportional error in a widely used glucose oxidase analyser: Impact for clinical research?
10.1111/cen.12274
000333912100025
23800101
Amati
F.
author
Broskey
N.T.
author
Carnero
E.A.
author
article
2014
Clinical Endocrinology
1365-2265
0300-0664
journal
80
5
768-770
Real time glycemia is a cornerstone for metabolic research, particularly when performing oral glucose tolerance tests (OGTT) or glucose clamps. From 1965 to 2009, the gold standard device for real time plasma glucose assessment was the Beckman glucose analyzer 2 (Beckman Instruments, Fullerton, CA), which technology couples glucose oxidase enzymatic assay with oxygen sensors. Since its discontinuation in 2009, today's researchers are left with few choices that utilize glucose oxidase technology. The first one is the YSI 2300 (Yellow Springs Instruments Corp., Yellow Springs, OH), known to be as accurate as the Beckman(1). The YSI has been used extensively for clinical research studies and is used to validate other glucose monitoring devices(2). The major drawback of the YSI is that it is relatively slow and requires high maintenance. The Analox GM9 (Analox instruments, London), more recent and faster, is increasingly used in clinical research(3) as well as in basic sciences(4) (e.g. 23 papers in Diabetes or 21 in Diabetologia). This article is protected by copyright. All rights reserved.
eng
60_published
SNF/Careers/PZ00P3-149398
SNF/Careers/PZ00P3-126339
true
Publication types: Letter
University of Lausanne
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