serval:BIB_C97ECEC4A9AE
Tuning In to Sound: Frequency-Selective Attentional Filter in Human Primary Auditory Cortex.
10.1523/JNEUROSCI.4405-12.2013
000314351300012
23365225
Da Costa
S.
author
van der Zwaag
W.
author
Miller
L.M.
author
Clarke
S.
author
Saenz
M.
author
article
2013
Journal of Neuroscience
1529-2401
0270-6474
journal
33
5
1858-1863
Cocktail parties, busy streets, and other noisy environments pose a difficult challenge to the auditory system: how to focus attention on selected sounds while ignoring others? Neurons of primary auditory cortex, many of which are sharply tuned to sound frequency, could help solve this problem by filtering selected sound information based on frequency-content. To investigate whether this occurs, we used high-resolution fMRI at 7 tesla to map the fine-scale frequency-tuning (1.5 mm isotropic resolution) of primary auditory areas A1 and R in six human participants. Then, in a selective attention experiment, participants heard low (250 Hz)- and high (4000 Hz)-frequency streams of tones presented at the same time (dual-stream) and were instructed to focus attention onto one stream versus the other, switching back and forth every 30 s. Attention to low-frequency tones enhanced neural responses within low-frequency-tuned voxels relative to high, and when attention switched the pattern quickly reversed. Thus, like a radio, human primary auditory cortex is able to tune into attended frequency channels and can switch channels on demand.
eng
60_published
true
Publication types: JOURNAL ARTICLE Publication Status: ppublish PDF type: Article
University of Lausanne
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