serval:BIB_AB27267DE8B5
Improving cardiometabolic and mental health in women with gestational diabetes mellitus and their offspring: study protocol for <i>MySweetHeart Trial</i>, a randomised controlled trial.
10.1136/bmjopen-2017-020462
000433129800040
29487077
Horsch
A.
author
Gilbert
L.
author
Lanzi
S.
author
Gross
J.
author
Kayser
B.
author
Vial
Y.
author
Simeoni
U.
author
Hans
D.
author
Berney
A.
author
Scholz
U.
author
Barakat
R.
author
Puder
J.J.
author
MySweetHeart Research Group
contributor
Barakat
R.
contributor
Berney
A.
contributor
Bovet
P.
contributor
Brand-Miller
J.
contributor
Chiolero
A.
contributor
Bernardo
S.D.
contributor
Dzemaili
S.
contributor
Epure
A.
contributor
Estoppey
S.
contributor
Gilbert
L.
contributor
Gonzalez-Rodriguez
E.
contributor
Gross
J.
contributor
Hans
D.
contributor
Horsch
A.
contributor
Kayser
B.
contributor
Lanzi
S.
contributor
Mivelaz
Y.
contributor
Puder
J.J.
contributor
Quansah
D.
contributor
Scholz
U.
contributor
Sekarski
N.
contributor
Simeoni
U.
contributor
Siddeek
B.
contributor
Vial
Y.
contributor
article
2018-02-27
BMJ open
2044-6055
2044-6055
journal
8
2
e020462
Gestational diabetes mellitus (GDM) carries prenatal and perinatal risk for the mother and her offspring as well as longer-term risks for both the mother (obesity, diabetes, cardiovascular disease) and her child (obesity, type 2 diabetes). Compared with women without GDM, women with GDM are twice as likely to develop perinatal or postpartum depression. Lifestyle interventions for GDM are generally limited to physical activity and/or nutrition, often focus separately on the mother or the child and take place either during or after pregnancy, while their results are inconsistent. To increase efficacy of intervention, the multifactorial origins of GDM and the tight link between mental and metabolic as well as maternal and child health need to be heeded. This calls for an interdisciplinary transgenerational approach starting in, but continuing beyond pregnancy.
This randomised controlled trial will assess the effect of a multidimensional interdisciplinary lifestyle and psychosocial intervention aimed at improving the metabolic and mental health of 200 women with GDM and their offspring. Women with GDM at 24-32 weeks gestational age who understand French or English, and their offspring and partners can participate. The intervention components will be delivered on top of usual care during pregnancy and the first year postpartum. Metabolic and mental health outcomes will be measured at 24-32 weeks of pregnancy, shortly after birth and at 6-8 weeks and 1 year after childbirth. Data will be analysed using intention-to-treat analyses. The <i>MySweetHeart Trial</i> is linked to the <i>MySweetHeart Cohort</i> (clinicaltrials.gov/ct2/show/NCT02872974).
We will disseminate the findings through regional, national and international conferences and through peer-reviewed journals.
NCT02890693; Pre-results.
depression
eating behavior
gestational diabetes mellitus
physical activity
social support
eng
60_published
true
peer-reviewed
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
University of Lausanne
mailto:serval_help@unil.ch
http://www.unil.ch/serval
http://serval.unil.ch/disclaimer
https://serval.unil.ch/notice/serval:BIB_AB27267DE8B5