serval:BIB_675332C00CE1
MRSA screening by the Xpert MRSA PCR assay: pooling samples of the nose, throat, and groin increases the sensitivity of detection without increasing the laboratory costs.
10.1007/s10096-012-1775-7
23143041
000316079200003
Blanc
D.S.
author
Nahimana
I.
author
Zanetti
G.
author
Greub
G.
author
article
2013
European Journal of Clinical Microbiology and Infectious Diseases
1435-4373
0934-9723
journal
32
4
565-568
The performance of the Xpert MRSA polymerase chain reaction (PCR) assay on pooled nose, groin, and throat swabs (three nylon flocked eSwabs into one tube) was compared to culture by analyzing 5,546 samples. The sensitivity [0.78, 95 % confidence interval (CI) 0.73-0.82] and specificity (0.99, 95 % CI 0.98-0.99) were similar to the results from published studies on separated nose or other specimens. Thus, the performance of the Xpert MRSA assay was not affected by pooling the three specimens into one assay, allowing a higher detection rate without increasing laboratory costs, as compared to nose samples alone.
eng
60_published
Publication types: Journal ArticlePublication Status: ppublish
University of Lausanne
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