serval:BIB_4923BD9DFC25
Toward a rational design of combination therapy in cancer.
10.1080/2162402X.2015.1046674
000361626500012
26451320
Doucey
M.A.
author
Xenarios
I.
author
article
2015
Oncoimmunology
2162-4011
2162-4011
journal
4
11
e1046674
By merging computational systems modeling and experimental approaches, we have uncovered treatments reprogramming pro-angiogenic monocytes present in breast tumor into immunologically potent cells capable of mediating an anti-tumor immune response. The unraveled pathways and ligands which underlie monocyte pro-angiogenic activity have a strong predictive value for breast cancer patient relapse - free survival.
eng
60_published
true
peer-reviewed
University of Lausanne
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