serval:BIB_215D122FF452
Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.
10.3390/nu9050517
000402054500095
28534852
Kosinski
C.
author
Jornayvaz
F.R.
author
article
review
2017-05-19
Nutrients
2072-6643
2072-6643
journal
9
5
0
The treatment of obesity and cardiovascular diseases is one of the most difficult and important challenges nowadays. Weight loss is frequently offered as a therapy and is aimed at improving some of the components of the metabolic syndrome. Among various diets, ketogenic diets, which are very low in carbohydrates and usually high in fats and/or proteins, have gained in popularity. Results regarding the impact of such diets on cardiovascular risk factors are controversial, both in animals and humans, but some improvements notably in obesity and type 2 diabetes have been described. Unfortunately, these effects seem to be limited in time. Moreover, these diets are not totally safe and can be associated with some adverse events. Notably, in rodents, development of nonalcoholic fatty liver disease (NAFLD) and insulin resistance have been described. The aim of this review is to discuss the role of ketogenic diets on different cardiovascular risk factors in both animals and humans based on available evidence.
Animals
Cardiovascular Diseases/etiology
Cardiovascular Diseases/prevention & control
Diabetes Mellitus, Type 2/complications
Diabetes Mellitus, Type 2/diet therapy
Diet, Ketogenic/adverse effects
Diet, Ketogenic/methods
Dietary Carbohydrates/administration & dosage
Humans
Insulin Resistance
Non-alcoholic Fatty Liver Disease/etiology
Obesity/complications
Obesity/diet therapy
Risk Factors
NAFLD
cardiovascular risk factors
fibroblast growth factor (FGF21)
insulin resistance
ketogenic diets
obesity
type 2 diabetes
eng
60_published
true
peer-reviewed
Publication types: Journal Article ; Review
Publication Status: epublish
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