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Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing.
10.1083/jcb.200809028
000264774800006
19307598
Chong
H.C.
author
Tan
M.J.
author
Philippe
V.
author
Tan
S.H.
author
Tan
C.K.
author
Ku
C.W.
author
Goh
Y.Y.
author
Wahli
W.
author
Michalik
L.
author
Tan
N.S.
author
article
2009
Journal of Cell Biology
1540-8140[electronic]
journal
184
6
817-831
Animals
Autocrine Communication
Cell Differentiation
Cell Proliferation
Cells, Cultured
Cytokines/metabolism
Epithelial Cells/enzymology
Epithelial Cells/immunology
Fibroblasts/enzymology
Fibroblasts/immunology
Gene Knockdown Techniques
Homeostasis
Humans
Intercellular Signaling Peptides and Proteins/metabolism
Interleukin 1 Receptor Antagonist Protein/genetics
Interleukin 1 Receptor Antagonist Protein/metabolism
Interleukin-1/genetics
Interleukin-1/metabolism
Interleukin-1alpha/metabolism
Interleukin-1beta/metabolism
MAP Kinase Kinase Kinases/metabolism
Mice
Mice, Knockout
Organ Culture Techniques
PPAR delta/deficiency
PPAR delta/genetics
PPAR-beta/deficiency
PPAR-beta/genetics
Paracrine Communication
Promoter Regions, Genetic
RNA Interference
Signal Transduction
Skin/enzymology
Skin/immunology
Time Factors
Transcription Factor AP-1/metabolism
Transcriptional Activation
Wound Healing
eng
60_published
true
peer-reviewed
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