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Inhibition of Wnt signalling and breast tumour growth by the multi-purpose drug suramin through suppression of heterotrimeric G proteins and Wnt endocytosis.
10.1042/BJ20150913
000374785000003
26604320
Koval
A.
author
Ahmed
K.
author
Katanaev
V.L.
author
article
2016
Biochemical Journal
1470-8728
0264-6021
journal
473
4
371-381
Animals
Antineoplastic Agents/pharmacology
Breast Neoplasms/metabolism
Breast Neoplasms/pathology
Cell Proliferation/drug effects
Endocytosis/drug effects
Female
HEK293 Cells
HeLa Cells
Heterotrimeric GTP-Binding Proteins/metabolism
Humans
Mice
Mice, Inbred NOD
Mice, SCID
Signal Transduction/drug effects
Suramin/pharmacology
Wnt3A Protein/metabolism
Xenograft Model Antitumor Assays
eng
60_published
true
peer-reviewed
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
https://serval.unil.ch/notice/serval:BIB_B64BFFC5D22C
https://serval.unil.ch/resource/serval:BIB_B64BFFC5D22C.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B64BFFC5D22C2
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