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Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex.
10.1038/85286
11224522
000167413800015
Kalergis
A.M.
author
Boucheron
N.
author
Doucey
M.A.
author
Palmieri
E.
author
Goyarts
E.C.
author
Vegh
Z.
author
Luescher
I.F.
author
Nathenson
S.G.
author
article
2001
Nature immunology
1529-2908
journal
2
3
229-234
Animals
Antigens/genetics
Antigens/immunology
Cytokines/biosynthesis
Half-Life
Histocompatibility Antigens Class I/genetics
Histocompatibility Antigens Class I/immunology
Hybridomas
Kinetics
Lymphocyte Activation
Mutagenesis, Site-Directed
Nucleocapsid/genetics
Nucleocapsid/immunology
Nucleocapsid Proteins
Peptides/genetics
Peptides/immunology
Receptors, Antigen, T-Cell/genetics
Receptors, Antigen, T-Cell/immunology
T-Lymphocytes, Cytotoxic/immunology
eng
60_published
peer-reviewed
Publication types: Journal Article ; Research Support, U.S. Gov't, P.H.S.
Publication Status: ppublish