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Atypical and secondary hemolytic uremic syndromes have a distinct presentation and no common genetic risk factors
10.1016/j.kint.2019.01.023
30982675
Le Clech
A.
author
Simon-Tillaux
N.
author
Provot
F.
author
Delmas
Y.
author
Vieira-Martins
P.
author
Limou
S.
author
Halimi
J. M.
author
Le Quintrec
M.
author
Lebourg
L.
author
Grange
S.
author
Karras
A.
author
Ribes
D.
author
Jourde-Chiche
N.
author
Rondeau
E.
author
Fremeaux-Bacchi
V.
author
Fakhouri
F.
author
article
2019-06
Kidney Int
1523-1755
0085-2538
journal
95
6
1443-1452
Adolescent
Adult
Aged
Aged, 80 and over
Antibodies, Monoclonal, Humanized/therapeutic use
Atypical Hemolytic Uremic Syndrome/*genetics/mortality/pathology/therapy
Child
Child, Preschool
Complement Activation/genetics
Complement Inactivating Agents/therapeutic use
Complement System Proteins/*genetics/immunology
Disease Progression
Female
France/epidemiology
Hemolytic-Uremic Syndrome/*etiology/mortality/pathology/therapy
Humans
Kidney/immunology/pathology
Kidney Failure, Chronic/*epidemiology/pathology
Male
Middle Aged
Plasmapheresis/statistics & numerical data
Registries/statistics & numerical data
Renal Dialysis/statistics & numerical data
Renal Insufficiency, Chronic/*epidemiology/pathology
Retrospective Studies
Risk Factors
Treatment Outcome
Young Adult
*complement
*eculizumab
*hemolytic uremic syndrome
*thrombotic microangiopathy
eng
60_published
Le Clech, Alice
Simon-Tillaux, Noemie
Provot, Francois
Delmas, Yahsou
Vieira-Martins, Paula
Limou, Sophie
Halimi, Jean-Michel
Le Quintrec, Moglie
Lebourg, Ludivine
Grange, Steven
Karras, Alexandre
Ribes, David
Jourde-Chiche, Noemie
Rondeau, Eric
Fremeaux-Bacchi, Veronique
Fakhouri, Fadi
eng
Comparative Study
Research Support, Non-U.S. Gov't
Kidney Int. 2019 Jun;95(6):1443-1452. doi: 10.1016/j.kint.2019.01.023. Epub 2019 Mar 15.