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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
10.1016/S1074-7613(00)80391-X
A1997YH55400013
9390694
Yeh
W. C.
author
Shahinian
A.
author
Speiser
D.
author
Kraunus
J.
author
Billia
F.
author
Wakeham
A.
author
de la Pompa
J. L.
author
Ferrick
D.
author
Hum
B.
author
Iscove
N.
author
Ohashi
P.
author
Rothe
M.
author
Goeddel
D. V.
author
Mak
T. W.
author
article
1997-11
Immunity
1074-7613
journal
7
5
715-25
Animals
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism
Cell Death/*drug effects
Cycloheximide/pharmacology
Enzyme Activation
Female
Hematopoietic Stem Cells/cytology
JNK Mitogen-Activated Protein Kinases
Liver/embryology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
*Mitogen-Activated Protein Kinases
NF-kappa B/*physiology
Protein Synthesis Inhibitors/pharmacology
Proteins/*physiology
Receptors, Tumor Necrosis Factor/*physiology
Signal Transduction
TNF Receptor-Associated Factor 2
Tumor Necrosis Factor-alpha/*pharmacology
60_published
true
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov