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Curtailed T-cell activation curbs effector differentiation and generates CD8<sup>+</sup> T cells with a naturally-occurring memory stem cell phenotype.
10.1002/eji.201646732
000409517900007
28671275
Zanon
V.
author
Pilipow
K.
author
Scamardella
E.
author
De Paoli
F.
author
De Simone
G.
author
Price
D.A.
author
Martinez Usatorre
A.
author
Romero
P.
author
Mavilio
D.
author
Roberto
A.
author
Lugli
E.
author
article
2017-09
European journal of immunology
1521-4141
0014-2980
journal
47
9
1468-1476
Adult Stem Cells/physiology
Animals
Antigens, CD/metabolism
CD8-Positive T-Lymphocytes/physiology
Cancer Vaccines/immunology
Cell Differentiation
Cell Proliferation
Cell Self Renewal
Cells, Cultured
Humans
Immunologic Memory
Immunophenotyping
Immunotherapy, Adoptive/methods
Interleukin-15/metabolism
Lymphocyte Activation
Mice
Mice, SCID
Neoplasms/immunology
Neoplasms/therapy
Phenotype
Receptors, Antigen, T-Cell/metabolism
Adoptive cell transfer
CD8+
Effector T cells
T memory stem cells
T-cell activation
eng
60_published
true
peer-reviewed
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
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