How can drug discovery for psychiatric disorders be improved?

Details

Serval ID
serval:BIB_FE4BEC272245
Type
Article: article from journal or magazin.
Collection
Publications
Title
How can drug discovery for psychiatric disorders be improved?
Journal
Nature Reviews. Drug Discovery
Author(s)
Agid Y., Buzsáki G., Diamond D.M., Frackowiak R., Giedd J., Girault J.A., Grace A., Lambert J.J., Manji H., Mayberg H., Popoli M., Prochiantz A., Richter-Levin G., Somogyi P., Spedding M., Svenningsson P., Weinberger D.
ISSN
1474-1776 (Print)
ISSN-L
1474-1776
Publication state
Published
Issued date
2007
Volume
6
Number
3
Pages
189-201
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Psychiatric disorders such as depression, anxiety and schizophrenia are leading causes of disability worldwide, and have a huge societal impact. However, despite the clear need for better therapies, and major advances in the understanding of the molecular basis of these disorders in recent years, efforts to discover and develop new drugs for neuropsychiatric disorders, particularly those that might revolutionize disease treatment, have been relatively unsuccessful. A multidisciplinary approach will be crucial in addressing this problem, and in the first Advances in Neuroscience for Medical Innovation symposium, experts in multiple areas of neuroscience considered key questions in the field, in particular those related to the importance of neuronal plasticity. The discussions were used as a basis to propose steps that can be taken to improve the effectiveness of drug discovery for psychiatric disorders.
Keywords
Consensus Development Conferences as Topic, Drug Design, Humans, Mental Disorders/drug therapy, Mental Disorders/physiopathology, Models, Biological, Practice Guidelines as Topic, Questionnaires, Signal Transduction/drug effects, Tranquilizing Agents/pharmacology, Tranquilizing Agents/therapeutic use
Pubmed
Web of science
Create date
11/09/2011 17:58
Last modification date
20/08/2019 16:28
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