Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Intraoperative radiotherapy in the multimodality approach to colorectal cancer.
Surgical Oncology Clinics of North America
Publication types: Journal Article ; ReviewPublication Status: ppublish
The addition of intraoperative radiotherapy (IORT) to the multimodality approach for the treatment of locally advanced and locally recurrent colorectal cancer seems to result in improvements in local control and long-term survival. Local control and survival are most likely in patients in whom a gross total resection is accomplished. Peripheral nerve is the dose-limiting structure for patients treated with IORT. Further improvements in local control require the addition of dose modifiers during external beam radiotherapy or IORT. Distant relapse remains problematic, and effective systemic therapy is necessary to significantly improve long-term survival.
Colectomy/methods, Colonic Neoplasms/pathology, Colonic Neoplasms/radiotherapy, Combined Modality Therapy, Humans, Intraoperative Period, Neoplasm Recurrence, Local, Neoplasm Staging, Neoplasm, Residual, Palliative Care/methods, Radiation Tolerance, Radiotherapy, Adjuvant/methods, Rectal Neoplasms/pathology, Rectal Neoplasms/radiotherapy
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