Probing functional groups at the gas-aerosol interface using heterogeneous titration reactions: a tool for predicting aerosol health effects?

Détails

Ressource 1Demande d'une copieEtat: Supprimée
Version: de l'auteur
ID Serval
serval:BIB_F81ADCAEAA4D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Probing functional groups at the gas-aerosol interface using heterogeneous titration reactions: a tool for predicting aerosol health effects?
Périodique
Chemphyschem
Auteur(s)
Setyan Ari, Sauvain Jean-Jacques, Guillemin Michel, Riediker Michael, Demirdjian Benjamin, Rossi Michel J.
ISSN
1439-7641 (Electronic)
ISSN-L
1439-4235
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
11
Numéro
18
Pages
3823-3835
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Résumé
The complex chemical and physical nature of combustion and secondary organic aerosols (SOAs) in general precludes the complete characterization of both bulk and interfacial components. The bulk composition reveals the history of the growth process and therefore the source region, whereas the interface controls--to a large extent--the interaction with gases, biological membranes, and solid supports. We summarize the development of a soft interrogation technique, using heterogeneous chemistry, for the interfacial functional groups of selected probe gases [N(CH(3))(3), NH(2)OH, CF(3)COOH, HCl, O(3), NO(2)] of different reactivity. The technique reveals the identity and density of surface functional groups. Examples include acidic and basic sites, olefinic and polycyclic aromatic hydrocarbon (PAH) sites, and partially and completely oxidized surface sites. We report on the surface composition and oxidation states of laboratory-generated aerosols and of aerosols sampled in several bus depots. In the latter case, the biomarker 8-hydroxy-2'-deoxyguanosine, signaling oxidative stress caused by aerosol exposure, was isolated. The increase in biomarker levels over a working day is correlated with the surface density N(i)(O3) of olefinic and/or PAH sites obtained from O(3) uptakes as well as with the initial uptake coefficient, γ(0), of five probe gases used in the field. This correlation with γ(0) suggests the idea of competing pathways occurring at the interface of the aerosol particles between the generation of reactive oxygen species (ROS) responsible for oxidative stress and cellular antioxidants.
Mots-clé
Vehicle Emissions , Aerosols , Particulate Matter , Oxidative Stress , Reactive Oxygen Species , Biological Markers , Surface Properties , Occupational Exposure
Pubmed
Web of science
Création de la notice
04/01/2011 10:57
Dernière modification de la notice
03/03/2018 22:51
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