Meningococcemie chronique et deficit en IgA chez un adolescent. [Chronic meningococcemia and IgA deficiency in an adolescent]

Details

Serval ID
serval:BIB_F811C6DC7A4A
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Meningococcemie chronique et deficit en IgA chez un adolescent. [Chronic meningococcemia and IgA deficiency in an adolescent]
Journal
Archives de Pediatrie
Author(s)
Farron  F., Cheseaux  J. J., Pelet  B.
ISSN
0929-693X (Print)
Publication state
Published
Issued date
02/1996
Volume
3
Number
2
Pages
149-51
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Feb
Abstract
BACKGROUND: Chronic meningococcemia, defined as a meningococcal septicemia without meningeal symptoms with persistence of fever for at least one week prior to any antibiotics, is uncommon. Its pathophysiology remains unclear and a defect in host immunity has been suggested. CASE REPORT: A 15 year-old adolescent was examined because he suffered from fever for 6 days, headache, arthralgias. A disseminated erythema led to consider the diagnosis of vascularitis that was confirmed by skin biopsy. At day 9, blood culture yielded Neisseria meningitis group B that was confirmed by a second blood culture; the CSF was normal and sterile. The patient was given ceftriaxone plus penicillin for 14 days and completely cured. A detailed analysis of the complement system was negative but the patient was found to be deficient in IgA. CONCLUSION: This is the first reported case in which chronic meningococcemia is associated with complete IgA deficiency.
Keywords
Adolescent Ceftriaxone/therapeutic use Cephalosporins/therapeutic use Chronic Disease Humans IgA Deficiency/*complications Male Meningococcal Infections/*complications/drug therapy/immunology Penicillins/therapeutic use
Pubmed
Web of science
Create date
25/01/2008 10:04
Last modification date
20/08/2019 16:24
Usage data