Meningococcemie chronique et deficit en IgA chez un adolescent. [Chronic meningococcemia and IgA deficiency in an adolescent]

Détails

ID Serval
serval:BIB_F811C6DC7A4A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Meningococcemie chronique et deficit en IgA chez un adolescent. [Chronic meningococcemia and IgA deficiency in an adolescent]
Périodique
Archives de Pediatrie
Auteur(s)
Farron  F., Cheseaux  J. J., Pelet  B.
ISSN
0929-693X (Print)
Statut éditorial
Publié
Date de publication
02/1996
Volume
3
Numéro
2
Pages
149-51
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Feb
Résumé
BACKGROUND: Chronic meningococcemia, defined as a meningococcal septicemia without meningeal symptoms with persistence of fever for at least one week prior to any antibiotics, is uncommon. Its pathophysiology remains unclear and a defect in host immunity has been suggested. CASE REPORT: A 15 year-old adolescent was examined because he suffered from fever for 6 days, headache, arthralgias. A disseminated erythema led to consider the diagnosis of vascularitis that was confirmed by skin biopsy. At day 9, blood culture yielded Neisseria meningitis group B that was confirmed by a second blood culture; the CSF was normal and sterile. The patient was given ceftriaxone plus penicillin for 14 days and completely cured. A detailed analysis of the complement system was negative but the patient was found to be deficient in IgA. CONCLUSION: This is the first reported case in which chronic meningococcemia is associated with complete IgA deficiency.
Mots-clé
Adolescent Ceftriaxone/therapeutic use Cephalosporins/therapeutic use Chronic Disease Humans IgA Deficiency/*complications Male Meningococcal Infections/*complications/drug therapy/immunology Penicillins/therapeutic use
Pubmed
Web of science
Création de la notice
25/01/2008 11:04
Dernière modification de la notice
03/03/2018 22:51
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