No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis
Details
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State: Public
Version: After imprimatur
License: Not specified
Serval ID
serval:BIB_F7EF24D12187
Type
PhD thesis: a PhD thesis.
Collection
Publications
Institution
Title
No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis
Director(s)
HAFEN Gaudenz
Codirector(s)
AUBERT John-David
Institution details
Université de Lausanne, Faculté de biologie et médecine
Publication state
Accepted
Issued date
2019
Language
english
Abstract
Abstract
Objective: Patients with cystic fibrosis are more susceptible than members of the general population to lung infections.
Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months’ period.
Results: Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
Objective: Patients with cystic fibrosis are more susceptible than members of the general population to lung infections.
Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months’ period.
Results: Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
Keywords
Cystic fibrosis, Pseudomonas aeruginosa, Primoinfection, Eradication protocol
Create date
15/08/2019 12:38
Last modification date
30/10/2023 9:50
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